Here is a listing of commonly used keyboard shortcuts in Animation Shop.

File
New Ctrl + N
Open Ctrl + O
Save Ctrl + S
Save As F12

Edit
Undo Ctrl + Z
Cut Ctrl + X
Copy Ctrl + C
Paste Into Selected Frame Ctrl + E
Paste As New Frames Ctrl + L
Paste As New Animation Ctrl + V
Select All Ctrl + A
Select None Ctrl + D

Window
Duplicate Animation Shift + D

Help
Help Topics F1